Résultats de la recherche - 11 results
Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay
specific analysis. Estrogenic activities ranged from 682 ± 66 pg E2 eq./dm2 to 3250 ± 400 pg E2 eq./dm2 for “worst case” extraction and from 347 ± 30 pg E2 eq./dm2 to 1350 ± 70 pg E2 eq./dm2 for migration ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
With an accuracy of 100%, when equivocal results were considered positive, the results showed that combining HepaRG ™ cells with a genotoxin-specific qPCR array can improve (geno)toxicological hazard ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
specific models, as demonstrated here for aromatic azo compounds, typically found in printed paper and board FCM. The strategy developed here can easily be applied to other groups of chemicals facing the ...
Printed paper and board food contact materials as a potential source of food contamination.
not covered by a specific European regulation. Several contamination issues have raised concerns towards potential adverse health effects caused by exposure to substances migrating from printed paper ...
Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.
non-intentionally added substances). For the listed substances, concentrations in the migration solutions were compared to their respective specific migration limits (SML) (when applicable). Migration of all ...
Study of the possible migration risks of food contact materials for children under 3 years
a selection of representative baby bottles. For migration testing, the use of simulants is prescribed in the legislation to mimic the testing of real foods. Specifically, a mixture of water-EtOH (50:50, v/v) is ...
Evaluation of the migration of chemicals from baby bottles under standardised and duration testing conditions.
below their respective specific migration limits (SML s). The reference experiment confirmed the migration of some of the compounds previously detected in the EU repetitive-use experiment, though at lower ...
Development and application of a non-target extraction method for the analysis of migrating compounds from plastic baby bottles by GC-MS.
(unknown) chemicals from food contact materials, with emphasis on baby bottles. In this context, the use of simulants is prescribed in the legislation to mimic the testing of real foods. Specifically, we ...
Evaluation of the migration of 15 photo-initiators from cardboard packaging into Tenax(®) using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).
internal standard. The presented method is validated in terms of matrix effect, specificity, linearity, recovery, precision and sensitivity, showing the method can detect all photo-initiators at very low ...
In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials
luciferase gene, as a reporter gene, and a DNA responsive element specific to the human oestrogen receptor. The biological activity of a chemical compound is monitored by the measurement of light emitted by ...