Characteristics of the antibiotic regimen that affect antimicrobial resistance in urinary pathogens

Last updated on 7-7-2021 by Daisy Tysmans

Public Access


Peer reviewed scientific article



Background Treatment duration, treatment interval, formulation and type of antimicrobial (antibiotic) are modifiable factors that will influence antimicrobial selection pressure. Currently, the impact of the route of administration on the occurrence of resistance in humans is unclear. Methods In this retrospective multi-center cohort study, we assessed the impact of different variables on antimicrobial resistance (AMR) in pathogens isolated from the urinary tract in older adults. A generalized estimating equations (GEE) model was constructed using 7397 Escherichia coli (E. coli) is…

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