Data analysis associated with the use of whole genome sequencing for subtyping of pathogenic microorganisms, Salmonella Typhimurium as a case study

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

Scientific poster, presentation or proceeding




As the cost of bacterial whole genome sequencing (WGS) by NGS continues to decline, its application for routine (sub)typing of pathogenic microorganisms quickly becomes a reality. NGS allows to examine relationships between different bacterial isolates of the same species at the highest possible resolution, which is essential for epidemiological surveillance and outbreak detection. However, it is still a largely unresolved question how to convert WGS data into information of sufficient quality to be reliably used for epidemiological characterization and discrimination, including the identif…

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