TY - JOUR T1 - Surrogate species selection for assessing potential adverse environmental impacts of genetically engineered insect-resistant plants on non-target organisms JF - GM Crops and Food: Biotechnology in Agriculture and the Food Chain Y1 - 2014 A1 - K. Carstens A1 - B. Cayabyab A1 - Adinda De Schrijver A1 - Gadaleta,P.G. A1 - R.L. Hellmich A1 - J. Romeis A1 - N. Storer A1 - F.H. Valicente A1 - M. Wach KW - biosafety KW - environmental risk assessment KW - non-target organisms KW - surrogate species KW - tiered testing AB -

Most regulatory authorities require that developers of genetically engineered insect-resistant (GEIR) crops evaluate the potential for these crops to have adverse impacts on valued non-target organisms (NTOs), i.e., organisms not intended to be controlled by the trait. In many cases, impacts to NTOs are assessed using surrogate species, and it is critical that the data derived from surrogates accurately predict any adverse impacts likely to be observed from the use of the crop in the agricultural context. The key is to select surrogate species that best represent the valued NTOs in the location where the crop is going to be introduced, but this selection process poses numerous challenges for the developers of GE crops who will perform the tests, as well as for the ecologists and regulators who will interpret the test results. These issues were the subject of a conference "Surrogate Species Selection for Assessing Potential Adverse Environmental Impacts of Genetically Engineered Plants on Non-Target Organisms" convened by the Center for Environmental Risk Assessment, ILSI Research Foundation. This report summarizes the proceedings of the conference, including the presentations, discussions, and the points of consensus agreed to by the participants.

VL - 5 CP - 1 U1 - 4352 M3 - http://dx.doi.org/10.4161/gmcr.26560 ER -