TY - JOUR T1 - Impact of a trace element supplementation programme on health and performance of cross-breed (Bos indicus x Bos taurus) dairy cattle under tropical farming conditions: a double-blinded randomized field trial36964 JF - J.Anim Physiol Anim Nutr.(Berl) Y1 - 2015 A1 - Dermauw,V. A1 - Dierenfeld,E. A1 - Du Laing,G. A1 - Buyse,J. A1 - Bernard Brochier A1 - Steven Van Gucht A1 - Luc Duchateau A1 - Janssens,G.P. KW - 0 KW - a KW - Animal KW - antibodies KW - Antibody KW - Antioxidant KW - article KW - AS KW - Belgium KW - Benefit KW - blood KW - Cattle KW - composition KW - conditions KW - d KW - Deficiency KW - effect KW - electronic KW - farms KW - Field KW - Group KW - health KW - i KW - immune response KW - Impact KW - Increase KW - intervention KW - IS KW - journal KW - Laboratories KW - milk KW - n KW - NUTRITION KW - observed KW - ON KW - parameters KW - performance KW - plasma KW - present KW - programme KW - protein KW - Proteins KW - Rabies KW - response KW - Score KW - serum KW - status KW - study KW - Supplementation KW - Thiobarbituric Acid Reactive Substances KW - time KW - treatment KW - Universities KW - university KW - urban KW - Vaccination KW - Yield AB - Small-scale urban dairy farms (n = 16) in and around Jimma, Ethiopia with cross-bred (Bos indicus x Bos taurus) cows were enrolled in a double-blinded intervention study to investigate the effect of a trace element supplementation programme on trace element status and milk concentrations as well as performance [body condition score (BCS), milk yield, leptin], milk composition, antioxidant status (ferric-reducing ability of plasma (FRAP), thiobarbituric acid-reactive substances (TBARS)], blood biochemistry, serum proteins and immune response (antibody titre upon rabies vaccination). The farms were allocated to a (1) placebo or (2) Cu, Zn, Se, Co and I supplementation treatment for 150 d. On days 0 and 120, four lactating cows per farm were sampled for milk and plasma, and on day 150 for serum, following primo-vaccination. Cu deficiency was present in 17% and marginal Se deficiency in 30% of initially sampled cows, while no Zn shortage was detected. Over 120 days, trace element supplementation caused a bigger increase in plasma Se and Cu concentrations, but also a larger decrease of plasma Fe concentrations. A larger increase in milk Se concentrations was observed in the supplemented group, whereas none of the other elements were affected. BCS decreased more over time in the supplemented group. None of the other parameters of performance and antioxidant status nor milk composition or blood biochemistry was affected by treatment. Antibody response to rabies vaccination did not differ between groups, whereas alpha1-globulins tended to be lower and beta-globulins tended to be higher in the supplemented group. In conclusion, despite improved Cu and Se status and Se concentrations in milk, cows on tropical urban dairy farms did not seem to benefit from trace element supplementation, with respect to the parameters investigated VL - 99 CP - 3 U1 - 39159 M3 - http://dx.doi.org/10.1111/jpn.12209 ER -