TY - JOUR T1 - Chromatography in the detection and characterization of illegal pharmaceutical preparations. JF - J Chromatogr Sci Y1 - 2013 A1 - Eric Deconinck A1 - Sacré, Pierre-Yves A1 - Patricia Courselle A1 - De Beer, Jacques O KW - chromatography KW - Counterfeit Drugs KW - Street Drugs KW - Substance Abuse Detection AB -

Counterfeit and illegal pharmaceutical products are an increasing worldwide problem and constitute a major challenge for analytical laboratories to detect and characterize them. Spectroscopic techniques such as infrared spectroscopy and Raman spectroscopy have always been the first methods of choice to detect counterfeits and illegal preparations, but due to the evolution in the seized products and the necessity of risk assessment, chromatographic methods are becoming more important in this domain. This review intends to give a general overview of the techniques described in literature to characterize counterfeit and illegal pharmaceutical preparations, focusing on the role of chromatographic techniques with different detection tools.

VL - 51 CP - 8 U1 - http://www.ncbi.nlm.nih.gov/pubmed/23377647?dopt=Abstract M3 - 10.1093/chromsci/bmt006 ER -