TY - JOUR T1 - Methodological considerations in injury burden of disease studies across Europe: a systematic literature review JF - BMC Public Health Y1 - 2022 A1 - Charalampous, Periklis A1 - Elena Pallari A1 - Vanessa Gorasso A1 - Elena von der Lippe A1 - Brecht Devleesschauwer A1 - Sara M. Pires A1 - Plass, Dietrich A1 - Jane Idavain A1 - Henry Ngwa Che A1 - Isabel Noguer A1 - Alicia Padron-Monedero A1 - Rodrigo Sarmiento A1 - Marek Majdan A1 - Ádám, Balázs A1 - Ala’a Alkerwi A1 - Seila Cilovic-Lagarija A1 - Benjamin Clarsen A1 - Barbara Corso A1 - Sarah Cuschieri A1 - Keren Dopelt A1 - Mary Economou A1 - Fischer, Florian A1 - Alberto Freitas A1 - Juan Manuel García-González A1 - Federica Gazzelloni A1 - Artemis Gkitakou A1 - Hakan Gulmez A1 - Paul Hynds A1 - Gaetano Isola A1 - Lea S Jakobsen A1 - Kabir, Zubair A1 - Katarzyna Kissimova-Skarbek A1 - Ann Kristin Knudsen A1 - Naime Meriç Konar A1 - Carina Ladeira A1 - Brian Lassen A1 - Aaron Liew A1 - Marjeta Majer A1 - Enkeleint A. Mechili A1 - Mereke, Alibek A1 - Lorenzo Monasta A1 - Stefania Mondello A1 - Joana Nazaré Morgado A1 - Evangelia Nena A1 - Edmond S. W. Ng A1 - Vikram Niranjan A1 - Iskra Alexandra Nola A1 - Rónán O’Caoimh A1 - Panagiotis Petrou A1 - Vera Pinheiro A1 - Miguel Reina Ortiz A1 - Silvia Riva A1 - Samouda, Hanen A1 - João Vasco Santos A1 - Cornelia Melinda Adi Santoso A1 - Milena Santric Milicevic A1 - Dimitrios Skempes A1 - Aana Catarina Sousa A1 - Speybroeck, Niko A1 - Fimka Tozija A1 - Brigid Unim A1 - Hilal Bektaş Uysal A1 - Fabrizio Giovanni Vaccaro A1 - Orsolya Varga A1 - Milena Vasic A1 - Francesco Saverio Violante A1 - Grant M.A. Wyper A1 - Polinder, Suzanne A1 - Juanita A. Haagsma KW - burden of disease KW - Burden of Injury KW - Disability-Adjusted Life Years KW - methodology KW - REVIEW AB -

Background: Calculating the disease burden due to injury is complex, as it requires many methodological choices. Until now, an overview of the methodological design choices that have been made in burden of disease (BoD) studies in injury populations is not available. The aim of this systematic literature review was to identify existing injury BoD studies undertaken across Europe and to comprehensively review the methodological design choices and assumption parameters that have been made to calculate years of life lost (YLL) and years lived with disability (YLD) in these studies.

Methods: We searched EMBASE, MEDLINE, Cochrane Central, Google Scholar, and Web of Science, and the grey literature supplemented by handsearching, for BoD studies. We included injury BoD studies that quantified the BoD expressed in YLL, YLD, and disability-adjusted life years (DALY) in countries within the European Region between early-1990 and mid-2021.

Results: We retrieved 2,914 results of which 48 performed an injury-specific BoD assessment. Single-country independent and Global Burden of Disease (GBD)-linked injury BoD studies were performed in 11 European countries. Approximately 79% of injury BoD studies reported the BoD by external cause-of-injury. Most independent studies used the incidence-based approach to calculate YLDs. About half of the injury disease burden studies applied disability weights (DWs) developed by the GBD study. Almost all independent injury studies have determined YLL using national life tables.

Conclusions: Considerable methodological variation across independent injury BoD assessments was observed; differences were mainly apparent in the design choices and assumption parameters towards injury YLD calculations, implementation of DWs, and the choice of life table for YLL calculations. Development and use of guidelines for performing and reporting of injury BoD studies is crucial to enhance transparency and comparability of injury BoD estimates across Europe and beyond.

VL - 22 CP - 1 M3 - 10.1186/s12889-022-13925-z ER -