%0 Journal Article %J Eur.J.Clin.Microbiol.Infect.Dis. %D 2003 %T Disseminated infection due to Cylindrocarpon (Fusarium) lichenicola in a neutropenic patient with acute leukaemia: report of a case and review of the literature36720 %A Rodriguez-Villalobos,H. %A Georgala,A. %A H. Beguin %A Heymans,C. %A Pye,G. %A Crokaert,F. %A M. Aoun %K 0 %K a %K acute %K Agent %K Agents %K Amphotericin B %K an %K Antifungal Agents %K article %K Belgium %K Bone Marrow %K Brussels %K Case %K case reports %K Cellulitis %K de %K Diagnosis %K drug therapy %K Drug Therapy,Combination %K Female %K Fluconazole %K Foot %K Foot Ulcer %K Fungemia %K Fusarium %K Humans %K im %K immunology %K INFECTION %K IS %K isolation & purification %K Itraconazole %K journal %K Ketoconazole %K leukaemia %K Literature %K microbiology %K Multiple %K Neutropenia %K Opportunistic Infections %K Patient %K Precursor Cell Lymphoblastic Leukemia-Lymphoma %K Print %K report %K reports %K REVIEW %K Risk Assessment %K SB - IM %K SKIN %K TESTING %K therapeutic use %K tomography,X-Ray computed %K treatment %K Treatment Outcome %X Described here is an unusual case of disseminated Cylindrocarpon lichenicola (Fusarium lichenicola) infection originating from a toenail lesion of a neutropenic woman with cellulitis of the foot and underlying acute leukaemia. A computed tomography scan of the chest showed multiple, ill-defined, nodular infiltrates with alveolar consolidation. The fungus was isolated from both the nail and the skin of the infected toe. Susceptibility testing revealed low minimum inhibitory concentrations for amphotericin B (0.78 micro g/ml) and voriconazole (1.56 micro g/ml) and high minimum inhibitory concentrations (>100 micro g/ml) for fluconazole, ketoconazole and itraconazole. The infection resolved after treatment with a total dose of 1 g of amphotericin B followed by oral itraconazole and bone marrow regeneration %B Eur.J.Clin.Microbiol.Infect.Dis. %V 22 %P 62 - 65 %8 0/1/2003 %G eng %N 1 %1 36720 %& 62 %R http://dx.doi.org/10.1007/s10096-002-0851-9