%0 Journal Article %J Arch Virol %D 1989 %T High titre Hog Cholera virus production on Cytodex 3 microcarrier cultures. %A Ann Brigitte Cay %A De Smet, A %A Dubois, N %A F. Koenen %K Animals %K Cells, Cultured %K Classical swine fever virus %K Dextrans %K Virus Cultivation %X

In an attempt to produce Hog Cholera virus (HCV) preparations of high titre, optimal growth and trypsinization conditions of PK-15 microcarrier cell cultures were defined. Infecting a PK-15 Cytodex 3 microcarrier culture with HCV increased the yield of virus more than 10 times compared with conventional monolayer culture in Roux flasks.

%B Arch Virol %V 105 %P 113-8 %8 1989 %G eng %N 1-2 %1 http://www.ncbi.nlm.nih.gov/pubmed/2470336?dopt=Abstract