%0 Journal Article %J Epidemiol Infect %D 1994 %T Epidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leukaemia virus in serum pools. %A K Knapen %A Pierre Kerkhofs %A Thiry, E %A Mammerickx, M %K Animals %K Antibodies, Viral %K Belgium %K Cattle %K Enzootic Bovine Leukosis %K Enzyme-Linked Immunosorbent Assay %K Leukemia Virus, Bovine %K Predictive Value of Tests %K Sensitivity and Specificity %X

Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of 145 serum pools, comprising from 3 to 48 individual sera. The sample was constituted according to the frequency distribution of the negative and positive pools analysed during a screening involving the whole cattle population of Belgium. Sensitivity and specificity were estimated to 88.9% and 100% and the predicted negative and positive values were 99.9% and 100%, respectively. These results indicate the use of serum pools is suitable for the detection of BLV infected herds in eradication campaigns.

%B Epidemiol Infect %V 113 %P 563-9 %8 1994 Dec %G eng %N 3 %1 http://www.ncbi.nlm.nih.gov/pubmed/7995365?dopt=Abstract