<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Birgit Mertens</style></author><author><style face="normal" font="default" size="100%">Simon, Coraline</style></author><author><style face="normal" font="default" size="100%">Melissa Van Bossuyt</style></author><author><style face="normal" font="default" size="100%">Onghena, Matthias</style></author><author><style face="normal" font="default" size="100%">Vandermarken, Tara</style></author><author><style face="normal" font="default" size="100%">Van Langenhove, Kersten</style></author><author><style face="normal" font="default" size="100%">Heidi Demaegdt</style></author><author><style face="normal" font="default" size="100%">Els Van Hoeck</style></author><author><style face="normal" font="default" size="100%">Joris Van Loco</style></author><author><style face="normal" font="default" size="100%">Karine Vandermeiren</style></author><author><style face="normal" font="default" size="100%">Covaci, Adrian</style></author><author><style face="normal" font="default" size="100%">Scippo, Marie-Louise</style></author><author><style face="normal" font="default" size="100%">Elskens, Marc</style></author><author><style face="normal" font="default" size="100%">Luc Verschaeve</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Investigation of the genotoxicity of substances migrating from polycarbonate replacement baby bottles to identify chemicals of high concern.</style></title><secondary-title><style face="normal" font="default" size="100%">Food Chem Toxicol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Food Chem Toxicol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Benzhydryl Compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Food Contamination</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Infant</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagens</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenols</style></keyword><keyword><style  face="normal" font="default" size="100%">Polycarboxylate Cement</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2016 Mar</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">137</style></number><volume><style face="normal" font="default" size="100%">89</style></volume><pages><style face="normal" font="default" size="100%">126-37</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Due to the worldwide concern that bisphenol A might act as an endocrine disruptor, alternative materials for polycarbonate (PC) have been introduced on the European market. However, PC-replacement products might also release substances of which the toxicological profile--including their genotoxic effects--has not yet been characterized. Because a thorough characterization of the genotoxic profile of all these substances is impossible in the short term, a strategy was developed in order to prioritize those substances for which additional data are urgently needed. The strategy consisted of a decision tree using hazard information related to genotoxicity. The relevant information was obtained from the database of the European Chemicals Agency (ECHA), in silico prediction tools (ToxTree and Derek Nexus(TM)) and the in vitro Vitotox(®) test for detecting DNA damage. By applying the decision tree, substances could be classified into different groups, each characterized by a different probability to induce genotoxic effects. Although none of the investigated substances could be unequivocally identified as genotoxic, the presence of genotoxic effects could neither be excluded for any of them. Consequently, all substances require more data to investigate the genotoxic potential. However, the type and the urge for these data differs among the substances.&lt;/p&gt;</style></abstract><custom1><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/26802677?dopt=Abstract</style></custom1><section><style face="normal" font="default" size="100%">126</style></section></record></records></xml>