<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hanquet, Germaine</style></author><author><style face="normal" font="default" size="100%">Tinne Lernout</style></author><author><style face="normal" font="default" size="100%">Vergison, Anne</style></author><author><style face="normal" font="default" size="100%">Verhaegen, Jan</style></author><author><style face="normal" font="default" size="100%">Kissling, Esther</style></author><author><style face="normal" font="default" size="100%">Tuerlinckx, David</style></author><author><style face="normal" font="default" size="100%">Malfroot, Anne</style></author><author><style face="normal" font="default" size="100%">Swennen, Béatrice</style></author><author><style face="normal" font="default" size="100%">Martine Sabbe</style></author></authors><translated-authors><author><style face="normal" font="default" size="100%">Belgian IPD Scientific Committee</style></author></translated-authors></contributors><titles><title><style face="normal" font="default" size="100%">Impact of conjugate 7-valent vaccination in Belgium: addressing methodological challenges.</style></title><secondary-title><style face="normal" font="default" size="100%">Vaccine</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Vaccine</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Belgium</style></keyword><keyword><style  face="normal" font="default" size="100%">Child, Preschool</style></keyword><keyword><style  face="normal" font="default" size="100%">Heptavalent Pneumococcal Conjugate Vaccine</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunization Schedule</style></keyword><keyword><style  face="normal" font="default" size="100%">incidence</style></keyword><keyword><style  face="normal" font="default" size="100%">Pneumococcal Infections</style></keyword><keyword><style  face="normal" font="default" size="100%">Pneumococcal Vaccines</style></keyword><keyword><style  face="normal" font="default" size="100%">Population Surveillance</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptococcus pneumoniae</style></keyword><keyword><style  face="normal" font="default" size="100%">Vaccination</style></keyword><keyword><style  face="normal" font="default" size="100%">Vaccines, Conjugate</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2011 Apr 05</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">29</style></volume><pages><style face="normal" font="default" size="100%">2856-64</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;In Belgium, the 7-valent pneumococcal conjugate vaccine (PCV7) was introduced into the national schedule in 2007. The early impact of PCV7 vaccination on paediatric invasive disease was estimated by comparing pre- and post-vaccination incidence from national surveillance. In children &lt;2 year-olds, vaccine-serotype incidence declined by 96% but non-vaccine-types increased 2-3-fold. Overall invasive disease decreased by 23-46%, depending on adjustment for under-reporting and pre-vaccine trends. Non-vaccine-types 1 and 19A had increased before PCV7 use, suggesting the contribution of other factors. Estimation of PCV7 impact comparing pre- and post-vaccination data should adjust for pre-vaccine trends, and serotype dynamics need further exploration.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">16</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/21342667?dopt=Abstract</style></custom1></record></records></xml>