<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cornelis A De Pijper</style></author><author><style face="normal" font="default" size="100%">Annefleur C Langedijk</style></author><author><style face="normal" font="default" size="100%">Sanne Terryn</style></author><author><style face="normal" font="default" size="100%">Steven Van Gucht</style></author><author><style face="normal" font="default" size="100%">Martin P Grobusch</style></author><author><style face="normal" font="default" size="100%">Abraham Goorhuis</style></author><author><style face="normal" font="default" size="100%">Cornelis Stijnis</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Long-term memory response after a single intramuscular rabies booster vaccination, 10-24 years after primary immunization.</style></title><secondary-title><style face="normal" font="default" size="100%">J Infect Dis</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Rabies</style></keyword><keyword><style  face="normal" font="default" size="100%">Vaccination</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021 Jan 27</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;b&gt;BACKGROUND: &lt;/b&gt;To date, published data regarding long-lasting immunological rabies memory after a pre-exposure prophylaxis (PrEP)-schedule are scarce. We tested the hypothesis that rabies booster immunization elicits rapid anamnestic responses.&lt;/p&gt;

&lt;p&gt;&lt;b&gt;METHODS: &lt;/b&gt;For this observational study, we included participants who had received PrEP 10-24 years before inclusion. We measured rabies antibody titers before, and on days 3, 7 and 14 after one single intramuscular booster.&lt;/p&gt;

&lt;p&gt;&lt;b&gt;RESULTS: &lt;/b&gt;All 28 participants responded adequately regardless route of administration or (2-dose vs. 3-dose) PrEP-regimen.&lt;/p&gt;

&lt;p&gt;&lt;b&gt;CONCLUSION: &lt;/b&gt;Rabies immunological memory is reactivated within 7 days after a single intramuscular booster immunization, even when administered 10-24 years after PrEP.&lt;/p&gt;
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