<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Declan Patrick Moran</style></author><author><style face="normal" font="default" size="100%">Sara Monteiro Pires</style></author><author><style face="normal" font="default" size="100%">Grant M. A. Wyper</style></author><author><style face="normal" font="default" size="100%">Brecht Devleesschauwer</style></author><author><style face="normal" font="default" size="100%">Sarah Cuschieri</style></author><author><style face="normal" font="default" size="100%">Zubair Kabir</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Estimating the direct Disability-Adjusted Life Years associated with SARS-CoV-2 (COVID-19) in the Republic of Ireland: The first full year</style></title><secondary-title><style face="normal" font="default" size="100%">International Journal of Public Health</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">burden of disease</style></keyword><keyword><style  face="normal" font="default" size="100%">COVID-19</style></keyword><keyword><style  face="normal" font="default" size="100%">DALY</style></keyword><keyword><style  face="normal" font="default" size="100%">Ireland</style></keyword><keyword><style  face="normal" font="default" size="100%">pandemic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Feb-06-2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">67</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Objectives: Burden of Disease frameworks facilitate estimation of the health impact of diseases to be translated into a single measure, such as the Disability-Adjusted-Life-Year (DALY).&lt;/p&gt;

&lt;p&gt;Methods: DALYs were calculated as the sum of Years of Life Lost (YLL) and Years Lived with Disability (YLD) directly associated with COVID-19 in the Republic of Ireland (RoI) from 01 March 2020, to 28 February 2021. Life expectancy is based on the Global Burden of Disease (GBD) Study life tables for 2019.&lt;/p&gt;

&lt;p&gt;Results: There were 220,273 confirmed cases with a total of 4,500 deaths as a direct result of COVID-19. DALYs were estimated to be 51,622.8 (95% Uncertainty Intervals [UI] 50,721.7, 52,435.8). Overall, YLL contributed to 98.5% of the DALYs. Of total symptomatic cases, 6.5% required hospitalisation and of those hospitalised 10.8% required intensive care unit treatment. COVID-19 was likely to be the second highest cause of death over our study’s duration.&lt;/p&gt;

&lt;p&gt;Conclusion: Estimating the burden of a disease at national level is useful for comparing its impact with other diseases in the population and across populations. This work sets out to standardise a COVID-19 BoD methodology framework for the RoI and comparable nations in the EU.&lt;/p&gt;
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