<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">David Triest</style></author><author><style face="normal" font="default" size="100%">Katherine Espinoza Rimachi</style></author><author><style face="normal" font="default" size="100%">Pauline Pauss</style></author><author><style face="normal" font="default" size="100%">Alexandra Vodolazkaia</style></author><author><style face="normal" font="default" size="100%">Katelijne Dierick</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Installment of the Sciensano biobanks and their data quality management : lessons learned from the practical implementation of data quality control measures</style></title><secondary-title><style face="normal" font="default" size="100%">Europe Biobank Week</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Control</style></keyword><keyword><style  face="normal" font="default" size="100%">data</style></keyword><keyword><style  face="normal" font="default" size="100%">LIMS</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality</style></keyword><keyword><style  face="normal" font="default" size="100%">Sample-registers</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2024</style></date></pub-dates></dates><publisher><style face="normal" font="default" size="100%">BBMRI-ERIC</style></publisher><pub-location><style face="normal" font="default" size="100%">Vienna, Austria</style></pub-location><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The biobanks of the Sciensano health institute&lt;br&gt;
were installed in accordance to the Belgian&lt;br&gt;
biobanking legislation of 2018. This in order to&lt;br&gt;
keep preserving and using Sciensano’s existing&lt;br&gt;
as well as future collections of human body&lt;br&gt;
material for scientific research. In 2020, the&lt;br&gt;
Central Biobank Platform (CBP) has been&lt;br&gt;
developed at Sciensano to support these divers&lt;br&gt;
Sciensano biobanks, having 171.345 samples of&lt;br&gt;
various types being currently preserved. Since&lt;br&gt;
its installment, the CBP has optimized the&lt;br&gt;
biobanking data management procedures and&lt;br&gt;
implemented various data quality control&lt;br&gt;
measures.&lt;/p&gt;

&lt;p&gt;After a requirements collection, a biobanking&lt;br&gt;
laboratory information management system&lt;br&gt;
with audit trail (SLIMS from Agilent) was&lt;br&gt;
introduced and configured for the Sciensano&lt;br&gt;
biobanks. Critical data fields were defined&lt;br&gt;
taking into account the applicable legislative&lt;br&gt;
framework as well as quality standards for these&lt;br&gt;
biobank registers (i.e. datasets). The ALCOA and&lt;br&gt;
FAIR principles were hereby followed. Several&lt;br&gt;
data security measures were also implemented&lt;br&gt;
in SLIMS together with CBP admin support and&lt;br&gt;
end-user trainings. Completeness and&lt;br&gt;
consistency of these biobank datasets is&lt;br&gt;
managed by defining rules and required field&lt;br&gt;
attributes as well as findable and reusable data&lt;br&gt;
by applying regular quality control checks.&lt;/p&gt;

&lt;p&gt;Several lessons were learned by the CBP over&lt;br&gt;
the years after introducing the SLIMS system for&lt;br&gt;
biobanking data management at Sciensano.&lt;br&gt;
One of the most important conclusions is that&lt;br&gt;
data entries can only be streamlined by applying&lt;br&gt;
a strategy including a close end-user support&lt;br&gt;
with regular data quality checks. Only then will&lt;br&gt;
high-quality data be maintained and be&lt;br&gt;
available for future research with biobanked&lt;br&gt;
samples.&lt;/p&gt;
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