VALGENT: A protocol for clinical validation of human papillomavirus assays.

Last updated on 30-8-2023 by Marie Malingreau

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Peer reviewed scientific article



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BACKGROUND: Testing for high-risk HPV is more effective in primary cervical cancer screening than the cytological examination of a Pap smear. Separate genotyping may be useful for triage in both HPV-based and cytology-based screening. Only clinically validated tests should be used in clinical practice.OBJECTIVES: VALGENT is a study framework for test comparison and validation of HPV assays in general and HPV genotyping tests in particular according to clinically relevant outcomes and for clinical applications endorsed by scientific evidence.STUDY DESIGN: VALGENT involves the collation of fr…

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