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Zoekresultaten - 4 results
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
Palma, Armando M; Tanchis, Federica; Goris, Nesya; Lefebvre, David; Kris De Clercq; Leyssen, Pieter; Lacroix, Céline; Pürstinger, Gerhard; Coutard, Bruno; Canard, Bruno; Boehr, David D; Arnold, Jamie J; ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Letellier, Carine; Froeyen, Matheus; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; De Clercq, Erik; Gueiffier, Alain; ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Chezal, Jean-Michel; Froeyen, Matheus; Leyssen, Pieter; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; Letellier, ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Rozenski, Jef; Gil, Laura H V G; Letellier, Carine; Lanford, Robert; Canard, Bruno; F. Koenen; Pierre Kerkhofs; Donis, Ruben O; Herdewijn, Piet; Watson, Julia; De Clercq, Erik; Puerstinger, Gerhard; Neyts, ...