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Zoekresultaten - 5 results
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Musiu, Simone; Pürstinger, Gerhard; Stallinger, Sylvia; Vrancken, Robert; Andy Haegeman; F. Koenen; Leyssen, Pieter; Froeyen, Mathy; ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Letellier, Carine; Froeyen, Matheus; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; De Clercq, Erik; Gueiffier, Alain; ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
Publication Type: Peer reviewed scientific article Authors: Vrancken, R; Paeshuyse, J; Andy Haegeman; Puerstinger, G; Froeyen, M; Herdewijn, P; Pierre Kerkhofs; Neyts, J; F. Koenen Source: Antiviral ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Chezal, Jean-Michel; Froeyen, Matheus; Leyssen, Pieter; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; Letellier, ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Leyssen, Pieter; Mabery, Eric; Boddeker, Nina; Vrancken, Robert; Froeyen, Matheus; Ansari, Israrul H; Dutartre, Hélène; ...