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Zoekresultaten - 97 results

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

result in CVD are not fully understood. To comprehensively describe and understand the pathways through which pollutant exposure leads to cardiotoxicity, a systematic mapping review of the available ...

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: Joint 3R Symposium, Brussels, Belgium (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment (IATA) pollutants Health Topics:  ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Martin Paparella Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to ...

Linking nanomaterial-induced mitochondrial dysfunction to existing adverse outcome pathways for chemicals.

Martens; Egon L Willighagen; Tomasz Puzyn; Mihaela Roxana Cimpan; Frauke Lemaire; Birgit Mertens; Maria Dusinska; Valerie Fessard; Peter H Hoet Source: ALTEX (2023) Abstract: The Adverse Outcome Pathway ...

Lumpy Skin Disease: A Systematic Review of Mode of Transmission, Risk of Emergence and Risk Entry Pathway.

Publication Type: Peer reviewed scientific article Authors: Bianchini, Juana; Simons, Xavier; Humblet, Marie-France; Saegerman, Claude Source: Viruses, Volume 15, Issue 8 (2023) Keywords: Animals Bison Books Buffaloes Cattle Disease Outbreaks Lumpy skin d ...

Development of an AOP-based IATA for genotoxicity

O Armant; C Pachoulide; H Bouwmeester; G Raitano; E Benfenati; E Wyrzykowska; M Stepnik; T Puzyn; M Audebert; Birgit Mertens Source: EEMGS meeting (2023) Keywords: adverse outcome pathways genotoxicity ...

A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing

association. Also, the underlying pathways of how lifestyle might affect our health are still under debate. Here, we studied the mediation of different health behaviours or lifestyle factors on mental health and ...

Residential green space in association with the methylation status in a CpG site within the promoter region of the placental serotonin receptor HTR2A

can modify epigenetic processes of cognition-related pathways in placental tissue, such as DNA-methylation of the serotonin receptor  HTR2A. HTR2A-methylation was determined within 327 placentas from ...

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