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Zoekresultaten - 247 results
Trends in Hospital Antibacterial Consumption in Belgium (2017-2021): Evaluating the Impact of the COVID-19 Pandemic
cephalosporins (J01DC), third-generation cephalosporins (J01DD), macrolides, lincosamides and streptogramins (J01F, excluding erythromycin J01FA01), and fluoroquinolones (J01MA). The compound annual growth rate ...
A Benchmark Dose-based strategy for evaluating the combined effects of genotoxic compounds
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Sanders; Roel Anthonissen; George Johnson; Tamara Vanhaecke; Birgit Mertens Source: BelTox Annual Meeting, Brussels, Belgium (2023) Keywords: benchmark dose modelling genotoxic ...
The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa
the development of an anti-virulence compound that targets the bacterial TCS. Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories ...
Pyrogen testing of phage therapeutic products
amoebocyte lysate (LAL) assay and the animal-friendly alternative, the recombinant factor C (rFC) test. However, other (non-endotoxin) pyrogenic substances including compounds of the gram-positive bacterial ...
Applicability of the DPRA on mixture testing: challenges and opportunities.
Keywords: Animal Testing Alternatives Animals Peptides Abstract: The in chemico direct peptide reactivity assay (DPRA) is validated to assess protein reactivity of chemical compounds, relating to the ...
Challenges in Drug Surveillance: Strengthening the Analysis of New Psychoactive Substances by Harmonizing Drug Checking Services in Proficiency Testing.
mainly unidentified compounds, presumably due to no up-to-date libraries, and/ or confusion between structural isomers, such as 3- and 4-chloroethcathinone, or structural analogs, such as MIPLA ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
study within the problematic of the spread of antimicrobial resistance in the environment. These organisms are genetically modified to enhance the production of a compound (e.g. enzymes, vitamins), and ...
Simultaneous Detection and Quantification of Aflatoxin M1, Eight Microcystin Congeners and Nodularin in Dairy Milk by LC-MS/MS
among infants and children. However, it is crucial to address the presence of multiple natural toxic compounds that may co-occur in dairy milk to ensure its safety prior to consumption. Aflatoxin M1 ...
Impact of experimental design factors on the potency of genotoxicants in in vitro test
Abstract: Previous studies have shown that differences in experimental design factors may alter the potency of genotoxic compounds in in vitro genotoxicity tests. Most of these studies used traditional ...
Quantitative risk assessment of allergens leaching from menstrual hygiene products.
determined with the QRA and could induce sensitization. In addition, although no sensitization is expected for the other three compounds, an allergenic reaction might be provoked in women who are already ...