Zoekresultaten - 5 results

Synthesis and anti-tubercular activity of N(2)-arylbenzo[g]isoquinoline-5,10-dione-3-iminium bromides.

= 28.51 μM, SI = 24.58) was selected as the most promising representative. Apart from the nano-molar anti-mycobacterial activity, the compound was able to target intracellular residing Mycobacterium ...

Anti-mycobacterial activity of 1,3-diaryltriazenes.

its potential as anti-tubercular agent. Several compounds were identified with sub-micro molar inhibitory concentrations against M. tuberculosis and other clinically relevant mycobacterial species such ...

2,4-Dialkyl-8,9,10,11-tetrahydrobenzo[g]pyrimido[4,5-c]isoquinoline-1,3,7,12(2H,4H)-tetraones as new leads against Mycobacterium tuberculosis.

/ AIDS pandemic, halting the tuberculosis epidemic is of paramount importance. As part of our program to design new 2-aza-anthraquinones with anti-mycobacterial activity, various ...

Biological evaluation of diazene derivatives as anti-tubercular compounds.

generation and spread of drug resistant strains, a problem exacerbated by co-infection with HIV demands further efforts in the investigation of novel classes of anti-tubercular compounds. A library of eight ...

1,4-diarylpiperazines and analogs as anti-tubercular agents: synthesis and biological evaluation36446

Volume 49, Number 101, p.95- 101 (2012) Keywords: 1 4-Diarylpiperazines Anti-mycobacterial activity cytotoxicity Mycobacterium tuberculosis Abstract: Despite progress in modern chemotherapy to combat ...

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