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Zoekresultaten - 12 results
Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation.
oxygen consumption. The INH-triggered ATP increase and bactericidal activity were strongly compromised by Q203 and bedaquiline, which inhibit mycobacterial cytochrome and FF ATP synthase, respectively. ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
a cluster of genes that encodes components of the FAS- II (fatty acid synthase II) complex, which is targeted by isoniazid. On the other hand, a remarkable down-regulation of the NADH-dehydrogenase (ndh) ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
synthase II) complex, which is targeted by isoniazid. On the other hand, a remarkable down-regulation of the NADH-dehydrogenase (ndh) cluster genes was noted. This can be assigned to the dependence of ...
FabR regulates Salmonella biofilm formation via its direct target FabB.
De Keersmaecker; Steenackers, Hans P Source: BMC Genomics, Volume 17, p.253 (2016) Keywords: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase Bacterial Proteins Biofilms Chromatin Immunoprecipitation ...
Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice.
C57BL Polyketide Synthases Vaccination Vaccines, DNA Vaccines, Synthetic Abstract: There is no effective vaccine against Buruli ulcer. In experimental footpad infection of C57BL /6 mice with M. ulcerans, ...
Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.
of interferon-γ and expression of the bactericidal enzyme inducible nitric oxide synthase were not affected. Collectively, our data suggest that early but not late neutrophil recruitment is essential ...
Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991
Proteins Benzoic Acid biosynthesis Clinical Dihydropteroate Synthase disease Diseases DRUG drugs electronic evidence Folate Folic Acid Folic Acid Antagonists Folic-acid Functional Gene Knockdown Techniques ...
Role of mutations in dihydrofolate reductase DfrA (Rv2763c) and thymidylate synthase ThyA (Rv2764c) in Mycobacterium tuberculosis drug resistance
n resistance Role SB- IM Tetrahydrofolate Dehydrogenase therapeutic use Thymidylate Synthase Tuberculosis Tuberculosis,Multidrug-Resistant Abstract: n Service: Bacterial diseases Maladies bactériennes ...
SYBR®Green qPCR screening methods for the presence of "35S promoter" and "NOS terminator" elements in food and feed products400
“Nopaline Synthase” terminator (tNOS) are the most represented generic recombinant elements in commercial genetically modified crops to date. A set of four new SYBR Service: Activités transversales en ...
Isolation and purification of a new kalimantacin/batumin-related polyketide antibiotic and elucidation of its biosynthesis gene cluster
electronic Engineering function functions gene Gene Knockdown Techniques Genes,Bacterial Genetic genetics genomic Group Hydroxymethylglutaryl-CoA Synthase im inactivation INFECTION infections IS isolation ...