Zoekresultaten - 49 results
A roadmap for regulatory implementation of in vitro models for evaluation of vaccine efficacy
Publication Type: Scientific poster, presentation or proceeding Authors: R. J. Vandebriel; L. Tesolin; K. Veenstra; K. Huber Source: EVI, Niagara falls, Canada (2023) Keywords: in vitro model ...
WP20 Regulatory. Workshop outcome, dissemination, gaps, and next steps: from models to showcases
Scientific posters, presentations and proceedings FOS Classification: 1.6 Biological sciences ...
A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing
using qPCR. Generalised linear mixed models were used while adjusting for a priori chosen covariates. RESULTS: The average age (SD) of the study population was 49.9 (17.5) years, and 48.8% were men. ...
Residential green space in association with the methylation status in a CpG site within the promoter region of the placental serotonin receptor HTR2A
these associations are already evident during foetal development. Similar biological signals shape the developmental processes in the foetal brain and placenta.Therefore, we hypothesize that green space ...
Considerations on the principles of development and manufacturing qualities of challenge agents for use in human infection models
Classification: 1.6 Biological sciences ...
Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide
outcome of computational modelling. In this study, we aim to identify nanodescriptor(s) and biological endpoint(s) capable of predicting the toxicity of titanium-di-oxide (TiO2) NM s, and demonstrate how ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Keywords: Biological Products Drug Development Human Experimentation Humans vaccines whole genome sequencing Abstract: Controlled human infection models can be helpful to study pathogenesis and immune ...
Modelling for Taenia solium control strategies beyond 2020
aimed at refining the post-2020 targets for control of T. solium for a new roadmap for neglected tropical diseases. In response, two groups working on taeniasis and cysticercosis mathematical models ...
Performance of in silico models for mutagenicity prediction of food contact materials
demonstrate that performance varies among the four models, but can be increased by applying a combination strategy. Furthermore, the importance of the applicability domain is illustrated. Limited performance to ...
MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.
study the impact of MALT1 on virus infection in the brain, using the attenuated ERA rabies virus in different models of MALT1 deficient mice. We reveal the importance of MALT1-mediated inflammation and ...