Zoekresultaten - 68 results

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance

Publication Type: Peer reviewed scientific article Authors: Laura Van Poelvoorde; Kevin Vanneste; Sigrid C.J. De Keersmaecker; Isabelle Thomas; Nina Van Goethem; Steven Van Gucht; Xavier Saelens; Nancy Roosens Source: Frontiers in Microbiology, Volume 13 ...

Targeted Chromosomal Barcoding Establishes Direct Genotype-Phenotype Associations for Antibiotic Resistance in Mycobacterium abscessus.

Gonzalo-Asensio, Jesús Source: Microbiol Spectr (2023) Abstract: A bedaquiline-resistant Mycobacterium abscessus isolate was sequenced, and a candidate mutation in the gene was identified as responsible for the ...

Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples

Roosens Source: Microorganisms, Volume 11, Issue 3 (2023) Keywords: SARS-CoV-2; omicron; VOC; mutation; RT-ddPCR; variant detection; wastewater surveillance Abstract: Wastewater-based surveillance can be ...

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance.

mainly focused on the hemagglutinin gene. Whole-genome sequencing (WGS) enables tracking mutations across all influenza segments allowing a better understanding of the epidemiological effects of intra- and ...

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

Walker; CRyPTIC Consortium; Seq&Treat Consortium; Derrick W Crook; Nazir Ismail; Timothy C Rodwell; Vanessa Mathys Source: Lancet Microbe, Volume 3, Issue 4 (2022) Keywords: Drug Resistance mutations ...

Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing

consensus genome sequence of the most abundant strain is taken into consideration for analysis, but multiple variant strains are now circulating in the population. Consequently, in diagnostic samples, ...

Strategy to Develop and Evaluate a Multiplex RT-ddPCR in Response to SARS-CoV-2 Genomic Evolution.

and reliable diagnostic testing to prevent and control the viral transmission. However, inaccurate results may occur due to false negatives (FN) caused by polymorphisms or point mutations related to the ...

Large diversity of linezolid-resistant isolates discovered in food-producing animals through linezolid selective monitoring in Belgium in 2019.

period. The presence of LR chromosomal mutations, transferable LR genes and their genetic organizations and other resistance genes, as well as LR isolate relatedness (from this study and the NCBI database) ...

Factors for severe outcomes following SARS-CoV-2 infection in people with cystic fibrosis in Europe.

estimate incidence, describe clinical presentation and investigate factors associated with severe outcomes using multivariable analysis. RESULTS: Up to December 31, 2020, 26 countries reported information on ...

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