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Zoekresultaten - 8 results

In vitro toxicity, genotoxicity and antigenotoxicity of Nigella sativa extracts from different geographic locations

include alkaloids, flavonoids, and terpenoids. Therefore their properties and biological effects may be different. We used the neutral red uptake test, the bacterial Vitotox and Ames assays and the ...

Overview of OECD Process to Evaluate Miniaturized Ames Assays

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: EMGS workshop “OECD Assessment of Miniaturized Ames Assays: Results and Recommendations”, Washington ...

Antimutagenicity, antioxidant activity and cytotoxicity of n-tetracosanol, eiocosanoic acid and arjunolic acid isolated from Combretum microphyllum (Combretaceae)

characterise the compounds responsible forthe antimutagenic potential of Combretum microphyllum.Methods: The methanol extract of C. microphyllum was evaluated for antimutagenicityin the Ames/microsome assay ...

Genotoxicity and antigenotoxicity testing of traditional medicinal plants

Publication Type: Dissertation Authors: Ti Thu Ha Nguyen Source: UA, Antwerp, Belgium, p.NA (2017) Accession Number: NA Keywords: Ames assay antigenotoxicity Comet Assay genotoxicity Micronucleus ...

Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

activity of Combretum microphyllum. METHODS: The methanol leaf extract of C. microphyllum was evaluated for antimutagenicity in the Ames/microsome assay using Salmonella typhimurium TA98. TA100 and TA102. ...

The correlation between antimutagenic activity and total phenolic content of extracts of 31 plant species with high antioxidant activity.

determined using the Folin-Ciocalteu colorimetric assay. The mutagenicity of 31 selected extracts was determined in the Ames test using Salmonella typhimurium strains TA98 and TA100. The antimutagenicity of ...

In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.

Abstract: Prior to the downstream development of chemical substances, including pharmaceuticals and cosmetics, their influence on the genetic apparatus has to be tested. Several in vitro and in vivo assays ...

High-throughput bacterial mutagenicity testing:VITOTOX assay.

Hoboken, NJ, USA, p.570 (2013) ISBN: 978-1-118-06563-1 Keywords: Ames test genotoxicity high throughput sceening toxicity Vitotox Manuscript versions:  DOI:  http://dx.doi.org/10.1002/9781118538203.ch11 ...

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