Zoekresultaten - 98 results
Strain-level characterization without culture enrichment? Easing and accelerating outbreak investigation using shotgun metagenomics facilitated with nanopore adaptive sampling
resolved. Shotgun metagenomics is a sequencing method involving the analysis of the genetic material directly extracted from a sample, without the need for an isolation of the bacteria. By sequencing and ...
Interim 2022/23 influenza vaccine effectiveness: six European studies, October 2022 to January 2023.
settings.MethodsAll studies used the test-negative design, but with differences in other study characteristics, such as data sources, patient selection, case definitions and included age groups. Overall and influenza ...
Effects of long-term exposure to 50 Hz magnetic fields on cell viability, genetic damage, and sensitivity to mutagen-induced damage.
exposure limits could result in adverse human health effects. In the present study, the effects of long-term MF exposure on three different study endpoints (cell viability, genetic damage, and sensitivity to ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
It was proven that whole genome sequencing has a higher resolution than any combination of tests carried out so far. But the isolation is not always possible, and it is time-consuming. A new method ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
genetic toxicology GENOMARK biomarker predictive toxicology human health risk assessment new approach methodologies (NAMs) Abstract: Transcriptomics-based biomarkers are promising new approach methodologies ...
Retrospective evaluation of routine whole genome sequencing of Mycobacterium tuberculosis at the Belgian National Reference Center, 2019.
bioinformatics workflow to determine the species and antimicrobial resistance. In this study, we retrospectively compare results obtained via WGS to conventional phenotypic and genotypic testing, for all Belgian ...
Frequency of Participation in External Quality Assessment Programs Focused on Rare Diseases: Belgian Guidelines for Human Genetics Centers.
OBJECTIVE: The aim of this project is to develop Belgian guidelines on the frequency of participation in quality controls for genetic testing in the context of rare diseases. METHODS: A group of experts ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
Keersmaecker Source: Int J Mol Sci, Volume 21, Issue 15 (2020) Keywords: Betacoronavirus Coronavirus Infections Databases, Genetic Genome, Viral Humans Open Reading Frames Pandemics Pneumonia, Viral ...
The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).
Republic of the Congo Drug Resistance Female Humans Malaria, Falciparum Male middle aged Mutation Plasmodium falciparum Polymorphism, Genetic Young adult Abstract: Artemisinin-based combination therapies ...
Molecular surveillance of anti-malarial drug resistance in Democratic Republic of Congo: high variability of chloroquinoresistance and lack of amodiaquinoresistance.
Preschool Chloroquine Democratic Republic of the Congo Dried Blood Spot Testing Drug Resistance Humans Infant Infant, Newborn Malaria, Falciparum Mass Screening Membrane Transport Proteins middle aged ...