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Zoekresultaten - 74 results

Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.

of structurally diverse secondary metabolites with toxic potential has been identified, but occurrence and relative proportion of the different metabolites in complex mixtures depend on strain, ...

Accelerating the (regulatory) uptake of New Approach Methodologies via the RE-Place project

assessment of chemical mixtures’, Issue BelTox, Brussels, Belgium (2023) Keywords: 3Rs alternative methods to animal testing animal testing Database NAMs new approach methodologies Regulatory uptake ...

A Benchmark Dose-based strategy for evaluating the combined effects of genotoxic compounds

Belgium (2023) Keywords: benchmark dose modelling genotoxicity mixtures Health Topics:  Food consumption and food safety Consommation et sécurité alimentaires Voedselconsumptie en –veiligheid Service:  ...

Towards Characterization and genotoxicity assessment of mycotoxin mixtures present in food.

Mertens Source: BelTox Annual Meeting, Brussels, Belgium (2023) Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Food consumption and food safety Consommation ...

Identification and characterization of inorganic food additives and pearlescent pigments in sprays for food decoration by STEM-EDX

mixtures, characterisation of the fraction of small particles, including the particle size distribution, is needed for each single constituent or each component in the mixture2. This is challenging for ...

Development, validation, and application of a multimatrix UHPLC-MS/MS method for quantification of Datura-type alkaloids in food

food, oilseeds, honey, and pulses consisted of a solid-liquid extraction with an acidified mixture of methanol and water, while an additional step of solid-phase extraction on a cation-exchange sorbent ...

Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements

commonly encountered in PFS claiming weight-loss as indication. However, PFS usually are composed of mixtures of different plants resulting into a not so straightforward approach for their detection. In ...

Mixtures of genotoxicants: does the principle of additivity apply?

Belgium (2023) Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Food consumption and food safety Consommation et sécurité alimentaires Voedselconsumptie en ...

Applicability of the DPRA on mixture testing: challenges and opportunities.

molecular initiating event of skin sensitization induction. According to OECD TG 442C, the DPRA is technically applicable to test multi-constituent substances and mixtures of known composition, even though ...

Mixtures of genotoxicants: does the principle of additivity apply?

Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

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