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Zoekresultaten - 122 results
Host transcriptome profiling for resistance against lumpy skin disease (LSD).
Dirk Jan Source: BMC Res Notes, Volume 18, Issue 1 (2025) Keywords: Animals Cattle Disease Resistance Gene Expression Profiling Gene Ontology Interleukin 1 Receptor Antagonist Protein Lumpy skin disease ...
Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies
genotoxic or non-genotoxic based on gene expression data. In addition, a high-content method to simultaneously assess several genotoxicity parameters (e.g. ɣH2AX, PH3,…) with the Cytek-Amnis ImageStream ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
bioactivities and estrogenic receptor (ER α) (ant)agonistic bioactivities in the respective CALUX (chemical activated luciferase gene expression) bioassays. The mutagenicity of the samples was investigated with ...
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.
expansion of infected CD8 T cells displaying effector and exhaustion gene signatures, including GZMA, GNLY, PD-1, and TOX2 expression. Then, among viral genes expressed in infected CD8 T cells, we uncovered ...
Immunogenicity and protective efficacy of a multivalent herpesvirus vectored vaccine against H9N2 low pathogenic avian influenza in chicken.
of recombinant herpesvirus of turkey, expressing the H9 hemagglutinin gene from low pathogenic avian influenza virus (LPAIV) H9N2 and the avian orthoavulavirus-1 (AOAV-1) (commonly known as Newcastle ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
* Source: Chem Res Toxicol, Volume 37, Issue 3 (2024) Keywords: Animals Biomarkers Cell Line DNA Damage Gene Expression Profiling Humans Transcriptome Abstract: To modernize genotoxicity assessment and reduce ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
were developed based on an extended reference dataset of 38 chemicals including existing as well as newly generated gene expression data. Both unsupervised and supervised machine learning algorithms were ...
Listeria monocytogenes isolates from Cornu aspersum snails: Whole genome-based characterization and host-pathogen interactions in a snail infection model.
strongly associated with cases of human infection. All isolates contained intact genes associated with invasion and infection while hypervirulent isolates are adapted to host environment, possessing genes ...
Staphylococcal enterotoxin gene cluster: prediction of enterotoxin (SEG and SEI) production and of the source of food poisoning based on Saβ typing.
using commercially available kits.Six genes (and), encoding putative and undetectable enterotoxins, are located on the enterotoxin gene cluster () which is part of the genomic island Saβ. These ...