Novel GMO-Based Vaccines against Tuberculosis: State of the Art and Biosafety Considerations. [1]
Peer reviewed scientific article
SCIENSANO
Auteurs
Amaya Leunda [2]; Aline Baldo [3]; Goossens, Martine [4]; Huygen, Kris [5]; Philippe Herman [6]; Marta Romano [7]Trefwoorden
Samenvatting:
Novel efficient vaccines are needed to control tuberculosis (TB), a major cause of morbidity and mortality worldwide. Several TB vaccine candidates are currently in clinical and preclinical development. They fall into two categories, the one of candidates designed as a replacement of the Bacille Calmette Guérin (BCG) to be administered to infants and the one of sub-unit vaccines designed as booster vaccines. The latter are designed as vaccines that will be administered to individuals already vaccinated with BCG (or in the future with a BCG replacement vaccine). In this review we provide up …