Zoekresultaten - 8 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

for all drugs except ethionamide (91·4%), moxifloxacin (91·6%) and ethambutol (93·3%). Only two resistance mutations were classified for bedaquiline, delamanid, clofazimine, and linezolid as prevalence ...

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

showing 94% concordance of implied regimen with that driven by phenotypic DST, higher than all other benchmarked tools. Health Topics:  Tuberculosis Tuberculose Tuberculose Manuscript versions:  DOI:  ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

(1,097/2,534) of all samples in 2016.ConclusionWe recommend inclusion of NTM in sentinel programmes. The large increase of false positive cultures is hypothesised to result from processing issues prior to arrival ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

long-term follow-up of XDR- TB cases treated with a regimen containing meropenem-clavulanate (M/Clav). DESIGN: Retrospective observational case series study at a single hospital. METHODS: All hospitalised ...

Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.

become an important determinant for TB control programs. However, sufficient financial means need to be available to perform all required epidemiological investigations. Health Topics:  Tuberculosis ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

cultures. In total 88.6% (172/194) of the samples were correctly identified on the species-level using a cut-off score of 1.8 and 91.75% (178/194) using a cut-off of 1.65. All samples of the Mycobacterium ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

resistance mutations, (b) do not distinguish living from dead cells, (c) ignore all intrinsic resistance mechanisms, and (d) ignore the influence of compensatory mutations. Objectives We introduce ...

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