Zoekresultaten - 48 results

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

efficiently identify pollutants of interest. The evidence will be integrated in novel Adverse Outcome Pathways to facilitate regulatory acceptance of non-animal methods for cardiotoxicity testing. The current ...

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity Integrated approaches to testing and assessment (IATA) Health ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; Birgit Mertens Source: 57th Congress of the European Soci ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; Birgit Mertens Source: Joint 3R Symposium, Brussels, Belg ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Martin Paparella Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to ...

A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance

Ritskes-Hoitinga; R. Gehring Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: Cardiotoxicity pollutants systematic review toxicological evidence ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...

Belgian Mosquitoes Are Competent for Japanese Encephalitis Virus and Readily Feed on Pigs, Suggesting a High Vectorial Capacity.

Publication Type: Peer reviewed scientific article Authors: Claudia Van den Eynde *; Sohier, Charlotte; Matthijs, Severine; De Regge, Nick Source: Microorganisms, Volume 11, Issue 6 (2023) Abstract:, a day-active mosquito known to feed aggressively on hum ...

Simultaneous Detection and Quantification of Aflatoxin M1, Eight Microcystin Congeners and Nodularin in Dairy Milk by LC-MS/MS

(AFM1), an emerging mycotoxin of interest, is a potential contaminant in the milk of animals who ingest aflatoxin B1 (AFB1). The toxin is regulated in the European Union under Commission Regulation No ...

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