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Zoekresultaten - 15 results
The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa
Koch, Matthias D; Lavigne, Rob Source: Microbiol Spectr (2023) Abstract: More and more isolates have become resistant to antibiotics like carbapenem. As a consequence, ranks in the top three of pathogens ...
Pyrogen testing of phage therapeutic products
these last years, with treatments provided to more than 100 patients, against more than 10 different bacterial species. Therapeutic phage products are produced in a bacterial host strain, hence pyrogen ...
Characterization of a Bacteriophage GEC_vB_Bfr_UZM3 Active against.
drug-resistant human pathogens, but cases of the refractory infections, caused by strains that are not susceptible to the common antibiotic regimes established for have been more frequently reported. ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
RT-qPCR methods were developed in January 2020 for initial in silico specificity evaluation and to verify whether the targeted loci are highly conserved. Now that more whole genome data have become ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
the study (‘sliding scale Good Manufacturing Practice’), and, hence, is much more open to speedy drug development than anticipated. Recommendations included: the development of guidelines for human ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.
validated. These methods could be used for routine analysis and enable a more in-depth characterization of SF-antimicrobials. According to their popularity as SF-antimicrobials, 31 antibiotics, 3 antibacterial ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market
(UHPLC- MS2) and diode array detection (UHPLC- DAD), respectively were developed and validated. These methods could be used for routine analysis and enable a more in-depth characterization of ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
been developed to detect and quantify these peptides. The emerging of more polar peptides however requires the introduction of other separation techniques. Therefore, we set out to develop and validate ...
A new approach to define acceptance limits for hematology in external quality assessment schemes.
(MCV), white blood cells (WBC), platelets and reticulocytes. More than 440,000 data were collected. The relation between the absolute value of the relative differences between reported EQA results and ...
The use of Stationary Phase Optimized Selectivity Liquid Chromatography for the development of herbal fingerprints to detect targeted plants in plant food supplements.
and more and more, these products are bought through internet. Often the products sold through internet are not registered or declared with a national authority, meaning that no or minimal quality ...