Zoekresultaten - 50 results
Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4
CXCL12-3Cit, and CXCL12-5Cit, in which Arg(8), Arg(8)/Arg(12)/Arg(20), or all five arginines were citrullinated, respectively. Replacement of only Arg(8) caused already impaired (30-fold reduction) CXCR4 binding ...
Identification of endomorphin-1 and endomorphin-2 binding sites in human mu-opioid receptor by antisense oligonucleotide strategy4389
Number 512, p.507- 512 (2008) Keywords: 0 a Aequorin ALL Analgesics Analgesics,Opioid analysis Animals antagonists & inhibitors article AS at Base Sequence Binding Sites Calcium Cell cells chemistry ...
Antagonist-radioligand binding to D2L-receptors in intact cells.
Dopamine D2 Spiperone Time Factors Abstract: D(2)-dopamine receptors mediate most of the physiological actions of dopamine and are important recognition sites for antipsychotic drugs. Earlier binding studies ...
Iron-induced oxidative stress in haemodialysis patients: a pilot study on the impact of diabetes98
in diabetic patients (P = 0.008). This increase was accompanied by the appearance of non-transferrin bound iron (5.91 +/- 1.33 micromol/l), a loss in plasma iron-binding antioxidant capacity and ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
J Virol, Volume 81, Issue 20, p.11046-53 (2007) Keywords: Animals Antiviral Agents Binding Sites Cattle Diarrhea Viruses, Bovine Viral Enzyme Inhibitors Models, Molecular Pestivirus Pestivirus Infections ...
Mu-opioid receptor ligands lack receptor subtype selectivity in the aequorin luminescence-based calcium assay4393
characterize the binding selectivity of the mu-opioid receptor ligands, endomorphin-1, endomorphin-2, and DAMGO, in the in vitro functional assay, based on the changes in intracellular calcium levels. For the ...
Target gene sequencing to characterize the penicillin G susceptibility of Neisseria meningitidis36789
paris Penicillin G Penicillin Resistance Penicillin-Binding Proteins pharmacology Phenotype polymerase chain reaction Print protein Proteins recombination Recombination,Genetic Research Research Support ...
Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2)4395
Volume 50, Issue 3, Number 520, p.512- 520 (2007) Keywords: 0 a Aequorin Agent Agents agonists Analgesics Animals antagonists & inhibitors article AS Binding Sites brain Calcium chemical synthesis ...
A novel method to quantify in vivo transferrin glycation: applications in diabetes mellitus
result results serum stress study Transferrin Type Universities university VARIABILITY Abstract: BACKGROUND: In vitro glycation of transferrin leads to increased oxidative stress by impairing iron-binding ...
A novel method to quantify in vivo transferrin glycation: applications in diabetes mellitus101
leads to increased oxidative stress by impairing iron-binding antioxidant capacity. The aim of this study is to develop a method to evaluate in vivo transferrin glycation in diabetes. METHODS: We adapted ...