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Zoekresultaten - 113 results

NextGEM: Next-Generation Integrated Sensing and Analytical System for Monitoring and Assessing Radiofrequency Electromagnetic Field Exposure and Health.

Colussi, Loek; Pruppers, Mathieu; Baaken, Dan; Bogdanova, Anna Source: Int J Environ Res Public Health, Volume 20, Issue 12 (2023) Keywords: Cell Phone Electromagnetic Fields environmental exposure Humans ...

Effects of long-term exposure to 50 Hz magnetic fields on cell viability, genetic damage, and sensitivity to mutagen-induced damage.

damage induced by known mutagens) were investigated in the human B lymphoblastoid (TK6) cell line. Cells were exposed to 50 Hz  MF at three selected magnetic flux densities (i.e., 10, 100, and 500 μT) for ...

Impact of experimental design factors on the potency of genotoxicants in in vitro test

that of more traditional statistical methods based on lowest observed genotoxic effect levels. When comparing the in vitro  MN results obtained in both cell lines with the BMD covariate approach, ...

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

composed of small or large agglomerates with similar dispersion medium composition. For in vitro testing, human bronchial epithelial (HBE), colon epithelial (Caco2) and monocytic (THP-1) cell lines were ...

Is aggregated synthetic amorphous silica toxicologically relevant?

stronger effects in all the cell lines than the aggregated suspension (AGGR). We then compared DE- AGGR with 2 suspensions fractionated from AGGR: the precipitated fraction (PREC) and the supernatant ...

NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program

in Belgium. DNA samples derived from cell line mixes and artificially mutated cell lines, designed to carry variants of clinical relevance occurring in solid tumors, hematological malignancies, and ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

In this manuscript, an optimized protocol for a combined in vitro comet/micronucleus study to investigate these effects in a human lymphoblastoid cell line (TK6) is provided including the description ...

Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation.

inhibition. The activity of isoniazid (INH), a key first-line bactericidal antituberculosis drug currently known to inhibit mycolic acid synthesis, becomes extremely poor under stress conditions, such as ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

replication. YB-1 depletion resulted in a 10-fold decrease in HIV-1 replication in different cell lines. Dissection of the replication defects revealed that knockdown of YB-1 is associated with a 2- to 5-fold ...

Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8 and CD4CD8 T Cells.

are particularly important in the first line defense against herpesviruses, including alphaherpesviruses. In addition to their ability to kill target cells and produce interferon-γ, porcine and human NK ...

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