Zoekresultaten - 54 results

Safety assessment of titanium dioxide (E171) as a food additive.

effects. With respect to genotoxicity, the Panel concluded that TiO particles have the potential to induce DNA strand breaks and chromosomal damage, but not gene mutations. No clear correlation was observed ...

CBD oils on the Belgian market: A validated MRM GC-MS/MS method for routine quality control using QuEChERS sample clean up

however, encountered for routine analyses due to the matrix complexity, high cost of cannabinoid standards and low Δ9- THC concentrations. An oily matrix could cause technical damages to analytical ...

Identification of flavouring substances of genotoxic concern present in e-cigarette refills

tested flavourings induced gene mutations and chromosome damage in vitro, whereas equivocal results were obtained for the fourth compound. Thus, although there is a legislative framework which excludes the ...

New QSAR models to predict chromosome damaging potential based on the in vivo micronucleus test

Emilio Source: Toxicology Letters, Volume 329, Number 84 (2020) Keywords: Chromosome damage genotoxicity In silico model In vivo micronucleus QSAR Abstract: A large number of computer-based prediction ...

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

exposed to these suspensions for 24 h and endpoints such as cytotoxicity, total glutathione, epithelial barrier integrity, inflammatory mediators and DNA damage were measured. Large agglomerates of 17 nm ...

Phytochemical screening, antioxidant, anticoagulant and in vitro toxic and genotoxic properties of aerial parts extracts of Fumaria officinalis L. growing in Tunisia

the bacterial Vitotox test. This was confirmed in the comet assay which was conducted on human C3A cells, except for the methanolic extract where DNA damage appeared to be significantly increased at ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

effects of long-term exposure to ELF-(E) MF s on the genetic material and the impact of long-term pre-exposure to ELF-(E) MF s on the sensitivity of cells to the damage induced by known mutagens are needed. ...

Confronting Risk of Bias in RF Bioeffects Research. Comments on Two Papers by Vijayalaxmi and Prihoda

https://doi.org/10.1667/ RR15478.1 In two meritorious published articles (1, 2), Vijayalaxmi and Prihoda reviewed 225 published laboratory studies with a total of 2,160 individual tests on genetic damage to mammalian cells ...

Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

with our hormonal system by binding to endocrine receptors, resulting in adverse health effects such as reproductive damage, developmental impairment, obesity, diabetes and cancers. The aim of this study ...

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