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Zoekresultaten - 19 results
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
MALT1-addicted cancers. Here, we study the impact of MALT1 deficiency on brain inflammation and disease development in response to infection of mice with the highly virulent CVS-11 rabies virus. We demonstrate ...
Allergic Asthma Favors Growth in the Lungs of Infected Mice.
the IL-4/ STAT6 signaling pathway and IL-10, and is maintained in IL-12- and IFN-γR-deficient mice. The effects of the sensitization protocol were also tested on and pulmonary infections. Surprisingly, ...
Do current fortification and supplementation programs assure adequate intake of fat-soluble vitamins in Belgian infants, toddlers, pregnant women, and lactating women?
A, D, E, and K intake was minor, except in toddlers. National fortification strategies should be investigated as an alternative or additional strategy to prevent vitamin D and A deficiency. There is ...
MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.
with autoimmunity and cancer, implicating MALT1 as a new therapeutic target. While MALT1 deficiency has been shown to protect against experimental autoimmune encephalomyelitis, nothing is known about the ...
Impact of caspase-1/11,-3,-7, or IL-1/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.
Moreover, absence of caspase-3, but not of caspase-1 and-11 or-7, partially inhibited virus-induced cell death of bone marrow-derived macrophages. Intranasal inoculation with CVS-11 of mice deficient for ...
Historical aspects of iodine deficiency control.
iodine deficiency are not limited to endemic goiter and cretinism. Iodine deficiency disorders include also increased neonatal death rate and decreased intellectual development, although these consequences ...
Incorporation of the influenza A virus NA segment into virions does not require cognate non-coding sequences.
incorporation of the viral segments was tested by real-time RT- PCR. An initial virus growth deficiency correlated to a specific defect in NA segment incorporation. Upon serial passages, growth properties were ...
Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.
recognized. Vaccination against all serotypes is necessary to protect susceptible animals and to prevent onward spread of the virus by insect vectors. In our previous studies, we generated replication-deficient ...
No Association between Elevated Thyroid-Stimulating Hormone at Birth and Parent-Reported Problem Behavior at Preschool Age.
Source: Front Endocrinol (Lausanne), Volume 7, p.161 (2016) Abstract: OBJECTIVES: Mild level of iodine deficiency during pregnancy may reduce maternal thyroid hormone production and supply to the fetus ...
Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis.
TM is postulated to be essential, some proviruses expressing fusion-deficient envelope proteins unexpectedly replicate at wild-type levels. Surprisingly also, a conserved N-linked glycosylation site of ...