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Zoekresultaten - 2 results

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

v and clinical Mtb strains on ten anti- TB drugs including Bedaquiline, Pyrazinamide and Delamanid was determined, to identify RNA Biomarkers. In a next phase, the RNA-based DST was developed in 96 well ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

a pressure of the recently approved delamanid is investigated. Total RNA sequencing revealed that the response to this bicyclic nitroimidazole shows many similarities with pretomanid, an anti-tuberculous drug ...

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