Zoekresultaten - 5 results
Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.
Here, we evaluated the Deeplex Myc- TB targeted deep sequencing assay for prediction of resistance to 13 anti-tuberculous drugs/drug classes, directly applicable on sputum. With MTBC DNA tests, the limit ...
Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination.
view of AMR gene localization, i.e., chromosomal or on a plasmid. Whole-genome and plasmid DNA extraction methods were compared, as were assemblies consisting of short reads (Illumina MiSeq), long reads ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
phenotypic Drug Susceptibility Testing (DST) of M. tuberculosis (Mtb), multiple DNA-based methods were successfully introduced over the last years. Although these are fast and sensitive, they (a) are based on ...
The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae.
Volume 10, Issue 1, p.e0117163 (2015) Keywords: Animals DNA, Viral Genome, Viral mice Myoviridae Phylogeny Pseudomonas aeruginosa Pseudomonas Infections Pseudomonas Phages Tandem Mass Spectrometry ...
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.
quinolone-resistance-determining regions (QRDR s) of DNA gyrase (gyrA) and DNA topoisomerase IV (parC), such that most strains carry three QRDR mutations which together confer resistance to ciprofloxacin. The majority of AMR genes ...