Zoekresultaten - 6 results

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

printed paper and board food contact material (FCM) substances for further in-depth safety evaluation. Within the strategy, focus was put on genotoxicity, a key toxicological endpoint when evaluating ...

Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay

Chemosphere, Volume 221, Number 106 (2019) Keywords: ERE-CALUX Estrogens FCM Food packaging; Paperboard Phthalates Abstract: Paperboard used as packaging, a non-inert material, can transfer chemicals into food. ...

Performance of in silico models for mutagenicity prediction of food contact materials

(FCM) constituents were chosen as study substances since many of these lack experimental data, making them an interesting group for in silico screening. Accuracy, sensitivity, specificity, positive ...

Coatings in food contact materials: Potential source of genotoxic contaminants?

regulation exists on chemicals used in coatings for food contact materials (FCM). Therefore, these substances need to comply with the general provisions of EU Regulation 1935/2004 and, if present, with ...

(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.

based on the combination of multiple (quantitative) structure-activity relationship ((Q) SAR) tools. Non-evaluated substances used in printed paper and board food contact materials (FCM) were selected for ...

Printed paper and board food contact materials as a potential source of food contamination.

materials (FCM) are estimated to be the largest source of food contamination. Apart from plastics, the most commonly used FCM are made of printed paper and board. Unlike their plastic counterparts, these are ...

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