Zoekresultaten - 68 results

QuilA-Adjuvanted T. gondii Lysate Antigens Trigger Robust Antibody and IFNγ+ T Cell Responses in Pigs Leading to Reduction in Parasite DNA in Tissues Upon Challenge InfectionImage

results show that both the vaccine candidate and the TLA immunization elicited strong serum IgG responses and elevated percentages of CD4 + CD8 + IFN γ+ T cells in T. gondii infected pigs. However, the TLA ...

Allergic Asthma Favors Growth in the Lungs of Infected Mice.

the IL-4/ STAT6 signaling pathway and IL-10, and is maintained in IL-12- and IFN-γR-deficient mice. The effects of the sensitization protocol were also tested on and pulmonary infections. Surprisingly, ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

progressive suppression of IFN-γ and IL-17 responses, and increased IL-10 production. Whole genome sequencing of the two virulent isolates with MST22 genotype and two avirulent isolates of genotype MST91 and ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection.

progressive suppression of IFN-γ and IL-17 responses, and increased IL-10 production. Whole genome sequencing of the two virulent isolates with MST22 genotype and two avirulent isolates of genotype MST91 and ...

Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8(+) Lymphocytes in a Heterologous Challenge Model.

antigens upon inoculation with both strains. The in vitro IFN-γ production by TLA-stimulated PBMC s was correlated with the infection dose and predominantly brought about by CD3 (+) CD4 (-) CD8 α(bright) ...

Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines

similar immune responses characterized by a production of antigen-specific IFN-γ and IL-17A. The immune responses induced by AraMM are dependent on the type of formulation. Indeed, AraMM in emulsion does ...

Field performance of six Mycobacterium avium subsp. paratuberculosis antigens in a 20 h interferon gamma release assay in Belgium

Marc Source: Veterinary Immunology and Immunopathology, Volume 189 (2017) Keywords: IFN-γ Johne’s disease Mycobacterium avium subsp. paratuberculosis Paratuberculosis Health Topics:  Animal health Santé ...

Pseudorabies virus isolates from domestic pigs and wild boars show no apparent in vitro differences in replication kinetics and sensitivity to interferon-induced antiviral status.

these cell lines with IFN α, IFN γ or a combination of both provoked similar plaque-reducing effects for all strains. In conclusion, our results indicate that isolates from domestic swine and wild boar ...

In silico epitope analysis of unique and membrane associated proteins from Mycobacterium avium subsp. paratuberculosis for immunogenicity and vaccine evaluation.

evaluated in IFN-γ release assay. In summary, eleven M. avium subsp. paratuberculosis proteins were identified by in silico analysis and need to be further evaluated for their immunodiagnostic and vaccine ...

Humoral and cell mediated immune responses to a pertussis containing vaccine in pregnant and nonpregnant women.

before vaccination. In contrast, proliferative and IFN-γ responses were increased to TT, PT, and FHA in nonpregnant women one month after vaccination, whereas in pregnant women only TT specific T cell ...

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