Zoekresultaten - 7 results

Humoral and cellular immune responses against SARS-CoV-2 after third dose BNT162b2 following double-dose vaccination with BNT162b2 versus ChAdOx1 in cancer patients.

Omicron. Subjects receiving heterologous boosting demonstrated increased spike-specific CD8 + T cells, including higher IFN γ and TNF α levels. CONCLUSIONS: In cancer patients who received double-dose ...

In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination.

in three different mouse strains. Eleven Mtb-antigens were recognised across TB-resistant and susceptible mice. Confirming previous human data, several Mtb-antigens induced cytokines other than IFN ...

QuilA-Adjuvanted T. gondii Lysate Antigens Trigger Robust Antibody and IFNγ+ T Cell Responses in Pigs Leading to Reduction in Parasite DNA in Tissues Upon Challenge InfectionImage

results show that both the vaccine candidate and the TLA immunization elicited strong serum IgG responses and elevated percentages of CD4 + CD8 + IFN γ+ T cells in T. gondii infected pigs. However, the TLA ...

Allergic Asthma Favors Growth in the Lungs of Infected Mice.

the IL-4/ STAT6 signaling pathway and IL-10, and is maintained in IL-12- and IFN-γR-deficient mice. The effects of the sensitization protocol were also tested on and pulmonary infections. Surprisingly, ...

Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.

Mycobacterium tuberculosis infected mice with culture filtrate antigens leads to the appearance of a high percentage of D(b) restricted IFN gamma synthesizing CD8 + T cell blasts. Transporter associated protein-2 ...

What are the immunologically active components of bacille Calmette-Guérin in therapy of superficial bladder cancer?

cytosol, purified polysaccharides as glucan or arabinomannan, purified native proteins from BCG culture filtrate, recombinant 22 kDa protein, phosphate transporter PstS-2 and-3 proteins). IFN-gamma, IL-12, ...

Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by bacillus Calmette-Guérin vaccination in H-2b mice

We show that they use the degranulation pathway (secretion of perforins and granzymes) as the main lytic mechanism of cytotoxicity and also secrete IFN-γ upon incubation with CF-pulsed macrophages. ...

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