Zoekresultaten - 6 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

interpretation. Its existence should encourage the implementation of molecular diagnostics by National Tuberculosis Programmes. Funding: UNITAID, Wellcome, MRC, BMGF. Health Topics:  Tuberculosis Tuberculose ...

Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification.

procedure or to MALDI- TOF system status in each centre. In conclusion, MALDI- TOF showed to be a highly reproducible method and suitable for its implementation for NTM  identification. Health Topics:  ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

shared mutation of tlyA is a drug resistance mutation and phylogenetic marker, the first of its kind in M tuberculosis sensu stricto. FUNDING: The Swiss Federal Office of Public Health, the University of ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

Abstract: Mycobacterium avium subsp. hominissuis (Mah) represents a health concern for humans and to a lesser extent for pigs, but its zoonotic potential remains elusive. Using multispacer sequence typing ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

MALDI- TOF MS and outcomes vary from 55% correct identifications to 97%2-4. In this study, we optimized an extraction protocol and evaluated its efficiency using the Brüker Biotyper system v3.0 for 194 ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

Remarkably, the most highly induced genes comprise poorly characterized genes for which functional characterization might hint to the target molecule(s) of delamanid and its exact mode(s) of action. Health ...

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