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The reduction of CSFV transmission to untreated pigs by the pestivirus inhibitor BPIP: a proof of concept.

Microbiol, Volume 139, Issue 3-4, p.365-8 (2009) Keywords: Animals Antiviral Agents Classical Swine Fever Classical swine fever virus Imidazoles Palatine Tonsil Pyridines Sus scrofa Viral Load Viremia Virus ...

Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.

Imidazoles Leukopenia Palatine Tonsil Pyridines Swine Viral Load Viremia Abstract: 5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine (BPIP) is a representative of a class of imidazopyridines with ...

Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.

Three-Dimensional Imidazoles Inhibitory Concentration 50 Models, Molecular Molecular Structure polymerase chain reaction Pyridines RNA Replicase RNA, Viral Sequence Analysis, DNA Structure-Activity Relationship Virus ...

A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.

Johan Source: J Virol, Volume 80, Issue 1, p.149-60 (2006) Keywords: Antiviral Agents Diarrhea Virus 1, Bovine Viral Drug Resistance, Viral Imidazoles Lethal Dose 50 Mutation Pestivirus Pyridines RNA ...

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