Zoekresultaten - 25 results

Assessment of hazards and risks associated with dietary exposure to mineral oil for the Belgian population

used as point of departure (PoD). Due to existing toxicological uncertainties, the margin of exposure (MOE) approach was applied. In all investigated scenarios, the MOE values were well above 100, ...

Identification of flavouring substances of genotoxic concern present in e-cigarette refills

2,5-dimethyl4-hydroxyl-3(2H)-furanone and transhexanal, there was a clear concern for in vivo genotoxicity. A selection of 4 out of the remaining 22 flavourings was tested in two in vitro genotoxicity assays. Three out of the four ...

Chemical and toxciological characterization of e-liquid cigarettes

PhD thesis was therefore to first determine the chemical composition of the liquids used in e-cigarettes (e-liquid) and next to investigate toxicological aspects of flavouring substances present in ...

Report on a New Opioid NPS: Chemical and In Vitro Functional Characterization of a Structural Isomer of the MT-45 Derivative DiphenpipenolAbstract

Stove, Christophe Source: Journal of Analytical Toxicology (2020) Service:  Médicaments et produits de santé Geneesmiddelen en gezondheidsproducten Medicines and health products Manuscript versions:  DOI:  ...

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

A toxicologically relevant definition of NM s is therefore not yet available, which affects not only the risk assessment process but also hinders the regulation of nano-products. In this study, we assessed the ...

In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

Gbaguidi, Fernand Source: Journal of Toxicology, Volume 2020 (2020) Abstract: Cymbopogon giganteus Chiov. (Poaceae) is a medicinal plant used to treat various diseases in traditional medicine in several ...

Is aggregated synthetic amorphous silica toxicologically relevant?

Godderis, Lode; Jan Mast; Lison, Dominique; Hoet, Peter H. Source: Particle and Fibre Toxicology, Volume 17, Issue 1 (2020) Keywords: Aggregates Biological activity In vitro toxicity nanomaterials synthetic ...

Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data

investigate physicochemical properties and in vitro (geno)toxicity with analytical chemistry. Both natural coagulants could significantly improve the physicochemical properties of the textile wastewater samples ...

Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays

Chemical Toxicology, Volume 145 (2020) Keywords: CALUX bioassay Endocrine disrupting compounds (EDCs) Environmental chemistry In vitro toxicology Polycyclic aromatic hydrocarbons (PAHs) Abstract: Polycyclic ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

not clear. We assessed the toxicological response to HNT s (NaturalNano (NN)) before and after surface etching (NN-etched). Potential cytotoxicity of the two HNT s was screened in vitro in MutaTMMouse ...

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