Zoekresultaten - 26 results
Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.
quinones altertoxin I (ATX-I), ATX- II, ATX- III, alterperylenol (ALP), and stemphyltoxin III (STTX- III) showed in vitro genotoxic and mutagenic properties. Of all identified Alternaria toxins, the ...
P20-10: Microcystin-LR and aflatoxin M1 contamination in dairy milk samples and their combined in vitro hepatotoxicity
Publication Type: Peer reviewed scientific article Authors: Mohamed F. Abdallah; Van Camp, C.; Recote, J. May; Wannes Van Hassel *; Julien Masquelier *; A. Rajkovic Source: Toxicology Letters, ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
shift towards a more human-relevant in vitro genotoxicity testing strategy without the use of experimental animals. Service: Évaluation des risques et de l'impact sur la santé Risico- en ...
In Silico Methods for Chromosome Damage.
addressed. For chromosome damage, i.e., the induction of structural or numerical chromosome aberrations, several in vitro and in vivo test methods are available. In order to rapidly collect toxicological data ...
Assessment of hazards and risks associated with dietary exposure to mineral oil for the Belgian population
used as point of departure (PoD). Due to existing toxicological uncertainties, the margin of exposure (MOE) approach was applied. In all investigated scenarios, the MOE values were well above 100, ...
Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide
the toxicological effects of TiO2 NM s in vitro. However, the agglomeration state of NM s can be potentially influenced by in vitro exposure conditions and such influences could be just a confounder in ...
Identification of flavouring substances of genotoxic concern present in e-cigarette refills
transhexanal, there was a clear concern for in vivo genotoxicity. A selection of 4 out of the remaining 22 flavourings was tested in two in vitro genotoxicity assays. Three out of the four tested flavourings ...
Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo
A toxicologically relevant definition of NM s is therefore not yet available, which affects not only the risk assessment process but also hinders the regulation of nano-products. In this study, we assessed the ...
Report on a New Opioid NPS: Chemical and In Vitro Functional Characterization of a Structural Isomer of the MT-45 Derivative DiphenpipenolAbstract
Christophe Source: Journal of Analytical Toxicology (2020) Service: Médicaments et produits de santé Geneesmiddelen en gezondheidsproducten Medicines and health products Manuscript versions: DOI: ...
In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin
Gbaguidi Source: Journal of Toxicology, Volume 2020 (2020) Abstract: Cymbopogon giganteus Chiov. (Poaceae) is a medicinal plant used to treat various diseases in traditional medicine in several African ...