Zoekresultaten - 32 results

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

A toxicologically relevant definition of NM s is therefore not yet available, which affects not only the risk assessment process but also hinders the regulation of nano-products. In this study, we assessed the ...

Report on a New Opioid NPS: Chemical and In Vitro Functional Characterization of a Structural Isomer of the MT-45 Derivative DiphenpipenolAbstract

Christophe Source: Journal of Analytical Toxicology (2020) Service:  Médicaments et produits de santé Geneesmiddelen en gezondheidsproducten Medicines and health products Manuscript versions:  DOI:  ...

In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

Gbaguidi Source: Journal of Toxicology, Volume 2020 (2020) Abstract: Cymbopogon giganteus Chiov. (Poaceae) is a medicinal plant used to treat various diseases in traditional medicine in several African ...

Is aggregated synthetic amorphous silica toxicologically relevant?

Lode; Jan Mast; Lison, Dominique; Hoet, Peter H. Source: Particle and Fibre Toxicology, Volume 17, Issue 1 (2020) Keywords: Aggregates Biological activity In vitro toxicity nanomaterials synthetic ...

Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data

investigate physicochemical properties and in vitro (geno)toxicity with analytical chemistry. Both natural coagulants could significantly improve the physicochemical properties of the textile wastewater samples ...

Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays

Chemical Toxicology, Volume 145 (2020) Keywords: CALUX bioassay Endocrine disrupting compounds (EDCs) Environmental chemistry In vitro toxicology Polycyclic aromatic hydrocarbons (PAHs) Abstract: Polycyclic ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

clear. We assessed the toxicological response to HNT s (NaturalNano (NN)) before and after surface etching (NN-etched). Potential cytotoxicity of the two HNT s was screened in vitro in MutaTMMouse lung ...

In vitro antigenotoxic activity, in silico ADME prediction and protective effects against aflatoxin B1 induced hepatotoxicity in rats of an Erythrina latissima stem bark extract

Hermans; Kenn Foubert Source: Food and Chemical Toxicology (2019) Keywords: antigenotoxicity Erythrina latissima In vivo antihepatotoxic activity Leguminosae Prenylated flavonoids Abstract: Stem bark of ...

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

printed paper and board food contact material (FCM) substances for further in-depth safety evaluation. Within the strategy, focus was put on genotoxicity, a key toxicological endpoint when evaluating ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...

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