Zoekresultaten - 16 results

Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.

Res, Volume 50, Issue 1 (2019) Keywords: Animals Chickens Gene Expression Regulation Genome, Viral Hemagglutination Inhibition Tests Immunity, Innate In Vitro Techniques Influenza A Virus, H9N2 Subtype ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

protease that mediates the activation of several innate and adaptive immune cells in response to multiple receptors, and therapeutic MALT1 targeting is believed to be a valid approach for autoimmunity and ...

Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8 and CD4CD8 T Cells.

(NK) cells belong to the innate immune system and play a central role in the defense against viral infections and cancer development, but also contribute to shaping adaptive immune responses. NK cells ...

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

Van Gucht Source: J Virol (2018) Keywords: MALT1 Rabies Abstract: MALT1 is involved in the activation of immune responses as well as in the proliferation and survival of certain cancer cells. MALT1 acts ...

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

L'Homme, Laurent; Sahb, Mohaned Mohammed; Potemberg, Georges; Legrand, Sylvie; Lang, Roland; Beyaert, Rudi; Piette, Jacques; Baird, Mark Stephen; Huygen, Kris; Marta Romano Source: J Innate Immun, Volume 9, ...

Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines

immune responses Mycolic Acids Trehalose dimycolate Tuberculosis Abstract: Tuberculosis remains among the most deadly health threats to humankind. This povertyrelated disease, caused by bacteria of the ...

Age-Dependent Differences in Pseudorabies Virus Neuropathogenesis and Associated Cytokine Expression.

and an associated immune response in the olfactory bulb. IMPORTANCE: It is well known that alphaherpesvirus infections of humans and animals result in more severe clinical disease in newborns than in ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

innate responses and contributing to the development of specific adaptive immune responses. Novel adjuvants have been developed based on agonists of PRR s. Areas covered: Lipid pathogen-associated ...

Infectious Bursal Disease: a complex host-pathogen interaction.

out the role of an exacerbated innate immune response during the early stage of the infection with upregulated production of promediators that will induce a cytokine storm. In the case of IBDV, ...

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