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Zoekresultaten - 169 results

The landscape of drug resistance in Plasmodium falciparum malaria in the Democratic Republic of Congo: a mapping systematic review

Source: Trop Med Health, Volume 51, Issue 1 (2023) Keywords: Antimalarial drug resistance Democratic Republic of Congo Malaria Molecular markers of drug resistance mutations Abstract: CONTEXT: The ...

Whole-Genome Sequencing-Based Screening of MRSA in Patients and Healthcare Workers in Public Hospitals in Benin.

From this collection, 27 high-quality WGS datasets were obtained, which carried numerous genes and mutations associated with antimicrobial resistance. The gene was detected in all the sequenced isolates. ...

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance

Publication Type: Peer reviewed scientific article Authors: Laura Van Poelvoorde; Kevin Vanneste; Sigrid C.J. De Keersmaecker; Isabelle Thomas; Nina Van Goethem; Steven Van Gucht; Xavier Saelens; Nancy Roosens Source: Frontiers in Microbiology, Volume 13 ...

Targeted Chromosomal Barcoding Establishes Direct Genotype-Phenotype Associations for Antibiotic Resistance in Mycobacterium abscessus.

Gonzalo-Asensio, Jesús Source: Microbiol Spectr (2023) Abstract: A bedaquiline-resistant Mycobacterium abscessus isolate was sequenced, and a candidate mutation in the gene was identified as responsible for the ...

Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.

a mutation such as E119V- NA is known, highly sensitive PCR-based genotypic assays can be used to identify the prevalence of such mutant influenza viruses in clinical samples. In this study, based on an ...

Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples

Roosens Source: Microorganisms, Volume 11, Issue 3 (2023) Keywords: SARS-CoV-2; omicron; VOC; mutation; RT-ddPCR; variant detection; wastewater surveillance Abstract: Wastewater-based surveillance can be ...

Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants

Publication Type: Peer reviewed scientific article Authors: Laura Van Poelvoorde *; François Dufrasne *; Steven Van Gucht *; Xavier Saelens; Nancy Roosens * Source: Current Issues in Molecular Biology, Volume 45, Issue 3 (2023) Health Topics:  Health and ...

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying blaSCO-1 and blaDHA-1 Combined with Permeability Defects

the presence of  blaSCO-1  and  blaDHA-1, combined with permeability defects caused by point mutations in an outer membrane porin (OmpK37). The presence of the  blaSCO-1  gene on a conjugative IncFIB(K) ...

PRECISION: the Belgian molecular profiling program of metastatic cancer for clinical decision and treatment assignment.

provide access to a targeted drug for patients whose tumors harbor actionable mutations in case the matched drug is not available through reimbursement or clinical trials in Belgium. Health Topics:  Cancer ...

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