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Zoekresultaten - 187 results
Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.
Combination Gene Dosage Genetic Markers Geography Haplotypes Humans Malaria, Falciparum Mutation Plasmodium falciparum Polymorphism, Genetic Protozoan Proteins Abstract: Malaria is a major public health problem ...
Genetically stable infectious Schmallenberg virus persists in foetal envelopes of pregnant ewes.
foetal envelopes is genetically stable since only a few mutations compared to the inoculum were found. This supports the hypothesis that persisting virus could start the infection of new hosts. Finally, ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations ...
Attenuation of RNA viruses by redirecting their evolution in sequence space.
Darby Canine Kidney Cells Orthomyxoviridae Infections Point Mutation virulence Abstract: RNA viruses pose serious threats to human health. Their success relies on their capacity to generate genetic ...
Positive epistasis of major low-cost drug resistance mutations rpoB531-TTG and katG315-ACC depends on the phylogenetic background of Mycobacterium tuberculosis strains.
epidemic. Here we analysed the transmission capacity of these strains in the context of their phylogenetic background and drug resistance mutations. The study collection included all multidrug resistant (MDR) ...
Model-Based Classification for Digital PCR: Your Umbrella for Rain.
of precision, both at individual partition level and at the level of the global concentration. We illustrate our method on genetically modified organism, inhibition, dynamic range, and mutation ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
Proteins Genotype Genotyping Techniques Humans Microbial Sensitivity Tests Mutant Proteins Mutation Mycobacterium Mycobacterium tuberculosis Rifampin Terminology as Topic Abstract: The rpoB gene codes for ...
Incorporation of the influenza A virus NA segment into virions does not require cognate non-coding sequences.
restored. Sequencing revealed that the replacing 5' NC sequence length drove the type of mutations obtained. With sequences longer than the original, point mutations in the coding region with or without ...
Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts
n-Tetracosanol Abstract: BACKGROUND: Mutations play a major role in the pathogenesis and development of several chronic degenerative diseases including cancer. It follows, therefore that antimutagenic compound may ...