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mycolyl acids

Zoekresultaten - 9 results

Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation.

target inhibition. The activity of isoniazid (INH), a key first-line bactericidal antituberculosis drug currently known to inhibit mycolic acid synthesis, becomes extremely poor under stress conditions, ...

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

Hypothesis Immunisation immunology Infectious Infectious diseases Institute IS journal mechanism mice MODEL Mycobacterium Mycobacterium tuberculosis Mycolic Acids ON Oxygen pathogenic production public public ...

Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines

immune responses Mycolic Acids Trehalose dimycolate Tuberculosis Abstract: Tuberculosis remains among the most deadly health threats to humankind. This povertyrelated disease, caused by bacteria of the ...

Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity

Laboratories medical MODEL Molecular Molecular biology Molecular Structure Mycobacterium Mycobacterium tuberculosis Mycolic Acids ON present public public health Public-health Pulmonary response Responses SB- IM ...

The immunodominant T-cell epitopes of the mycolyl-transferases of the Antigen 85 complex of M. tuberculosis34076

Infectious diseases Institute IS journal M mice MODEL models Mycobacterium Mycobacterium bovis Mycobacterium ulcerans Mycolic Acids Patient patients Peptides production PROGRAM Programs protein Proteins public ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

Mutation Mycobacterium bovis Mycobacterium tuberculosis Mycolic Acids Organ Specificity Oxygen Species Specificity Spleen Th1 Cells Th17 Cells Trachea Treatment Outcome Tuberculosis Vaccination virulence ...

Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice

Keywords: acid Acids Activity ALL an AS Cell Cell Wall Class Deficiency Development DRUG effect effects Establish function Functional Genetic immune response in vivo INFECTION IS IT M M.tuberculosis,mycolic ...

Carbon source-induced modifications in the mycolic acid content and cell wall permeability of Rhodococcus erythropolis E1.

Sensitivity Tests Mycolic Acids Permeability Rhodococcus Rifampin Surface Tension Terpenes Tetracycline Abstract: The influence of the carbon source on cell wall properties was analyzed in an efficient ...

Influence of the growth substrate on the mycolic acid profiles of mycobacteria.

Environmental Cell Wall Chromatography, High Pressure Liquid Mycobacterium Mycolic Acids Polycyclic Aromatic Hydrocarbons Abstract: The influence of growth substrates on mycolic acid profiles of PAH-degrading ...

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